Prosaikogenin G

Research use only, not for human use.

Prosaikogenin G is a compound isolated from the roots of Buleurum bicaule Helm (Apiaceae) and id a derivative of Saikosaponin d in the gastrointestinal tract, exhibiting a significant inhibitory effect on angiotensin II-induced proliferation of mesangial

Prosaikogenin G is a compound isolated from the roots of Buleurum bicaule Helm (Apiaceae) and id a derivative of Saikosaponin d in the gastrointestinal tract, exhibiting a significant inhibitory effect on angiotensin II-induced proliferation of mesangial(In Vitro):Prosaikogenin?G holds a protective effect on the kidney for their down-regulated activity to angiotensin II (1 μM)-induced rat mesangial cell line (MC) proliferation at contentration of 25 or 50 μM, and does not rendered injury to the normal MC .

Prosaikogenin G (25, 50 μM) has protective action on the kidney for their down-regulated activity to the rat mesangial cell line (MC) proliferation induced by Ang II (1 μM), and does not exhibit injury to the normal MC.

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Endocrinology/Hormones

RAAS

RAAS

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99365-23-8

618.84

C36H58O8

>98% (HPLC)

In Vitro:?DMSO : 50 mg/mL (80.80 mM)

C[C@H]1O[C@@H](O[C@H]2CC[C@@]3(C)[C@@H](CC[C@]4(C)[C@@H]3C=C[C@]35OC[C@@]6(CCC(C)(C)C[C@@H]36)[C@H](O)C[C@@]45C)[C@]2(C)CO)[C@H](O)[C@@H](O)[C@H]1O

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(-20℃)

With Ice Pack

≥ 2 years